Conceptual understanding of the quantitative methods used to synthesize evidence. Methods for pooling evidence across independent studies, pooling binary/continuous outcomes, differences between fixed and random effects models, and guidelines for appraising published systematic reviews/meta-analyses. Prerequisites: either introductory level courses in statistics, epidemiology, or biostatistics or permission of instructor Offered: jointly with BIME 541/HSERV 529/PHARM; Spring