BIOST 550 Statistical Genetics I: Mendelian Traits
Mendelian genetic traits. Population genetics; Hardy-Weinberg, allelic variation, subdivision. Likelihood inference, information and power; latent variables and EM algorithm. Pedigree relationships and gene identity. Meiosis and recombination. Linkage detection. Multipoint linkage analysis. Prerequisites: STAT 390 and STAT 394, or permission of instructor. Offered: jointly with STAT 550; Spring