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Category:Research
Researchers identify a subset of patients with early melanoma who face a very low risk of dying from the disease
eCancer,
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Melanoma is the most serious type of skin cancer, but most patients have high chances of surviving the disease. In addition, there is evidence that melanoma is being diagnosed in patients who would never experience symptoms.  This study sought to identify early-stage melanoma patients with near-zero risk of death from melanoma.

“Not only are the results potentially practically useful, our simple models are highly interpretable and suggest insights into when melanoma is more or less dangerous for a patient,” said Kathleen Kerr, a study co-author and professor of biostatistics at the University of Washington School of Public Health.

in Research

In genetic research and medicine, scientists examining how common or rare a DNA variant is in a set of individuals often want to group people in a particular way — by geography, ancestry group, or some clinical characteristic — groupings that are referred to as stratified allele frequencies.

in Research
Newly defined biomarker may accelerate clinical trials for vaccines to prevent HIV-1 infection
HIV Vaccine Trials Network,
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A study published in the Aug. 22, 2022, issue of Nature Medicine identifies a new biomarker that appears effective as a surrogate endpoint to reliably predict the ability of broadly neutralizing monoclonal antibodies to prevent acquisition of HIV-1, the most common type of the virus that causes AIDS. Fred Hutch researchers Peter Gilbert, a research professor of biostatistics at the University of Washington School of Public Health, and Yunda Huang, a UW affiliate associate professor of global health, are the paper’s co-first authors.

in Research

Second opinions are believed to give both patients and physicians better insight into medical diagnoses and help them make better decisions about care and treatment.

in Research
Dementia risk screening tool shows promise in health care setting
Kaiser Permanente Washington Health Research Institute,
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In a new study, a tool to help discover undiagnosed dementia performed well in 2 separate health systems. “Around 50% of people living with dementia are undiagnosed,” said lead author Yates Coley, PhD, assistant biostatistics investigator at Kaiser Permanente Washington Health Research Institute (KPWHRI) and an affiliate assistant professor of biostatistics at the University of Washington.

in Research
COVID FINDINGS — WITH SOME CONTROVERSY
College of Arts & Sciences,
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When the World Health Organization (WHO) published an estimate of excess deaths worldwide during the COVID pandemic, Jon Wakefield expected some media interest. He did not anticipate a deluge of news stories and interview requests about the findings.

in Research
"Too often, lack of clarity in how genetics research is communicated can lead to a misunderstanding of its relationship to race. Attributing racial categories to genetic conditions is the opposite of precision medicine, leads to real harms for patients, and obscures the true causes of racial disparities in health." — Stephanie Gogarten, co-first author and research scientist with the Genetics Analysis Center
in Research

An estimated 60% of known infectious diseases and up to 75% of emerging infectious diseases are zoonotic in origin, meaning the disease is transmitted from animals to humans.

in Research