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Category:Research News

Key Alzheimer’s gene acts differently in non-Europeans

UW Medicine Newsroom
November 12, 2019
Study has implications for the use of personalized genetic risk in populations with diverse ancestries.Timothy Thornton, associate professor of biostatistics at the UW School of Public Health is senior author and co-authors include Andréa Horimoto, acting instructor of biostatistics and Ellen Wijsman, UW professor of medicine and biostatistics.
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Ancestry-specific genetic variation at APOE Alzheimer’s gene modifies disease risk

UW School of Public Health
November 8, 2019
In a new study of more than 3,000 Caribbean Hispanics, researchers from the University of Washington found that individuals with African ancestry at a key Alzheimer’s gene had 39 percent lower odds of developing Alzheimer’s disease than individuals with European ancestry at the gene. “The results from our study have important implications for the use of personalized genetic risk in populations with diverse ancestries, even for well-established risk factors,” said senior author Tim Thornton, associate professor of biostatistics at the UW School of Public Health.
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Controversial ‘gay gene’ app provokes fears of a genetic Wild West

Nature
October 30, 2019
Studies by Sarah Nelson (PHG, PhD ’18), a research scientist with the Genetic Analysis Center in the Department of Biostatistics, are cited in a recent Nature News article about a controversial third-party interpretation app based on a genetic study of same-sex sexual behavior. “While the app has since been taken down, it portends a growing trend for app developers to prematurely roll out potentially sensitive science in the interest of interpreting individual genomes,” says Nelson.
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Mathematical Model Could Help Correct Bias in Measuring Bacterial Communities

North Carolina State University News
September 13, 2019
A new mathematical model developed at North Carolina State University in partnership with Assistant Professor of Biostatistics Amy Willis from the University of Washington is profile in this story. Their work highlights a new calibration tool they developed that shows how bias distorts results when measuring bacterial communities through metagenomic sequencing.
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Following a low-fat diet can lead to several health benefits for women

Consumer Affairs
September 9, 2019
A new study conducted by researchers from the Fred Hutchinson Cancer Research Center found that women who follow diets that are low in fat can yield serious health benefits over time, including preventing the onset of serious diseases. “The [Women’s Health Initiative’s] Dietary Modification Trial has provided women with nutrition and disease prevention insights for some years,” said Dr. Ross Prentice, Fred Hutch researcher and UW Professor of Biostatistics.
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NSF funds novel tools for combining datasets with missing information

UW School of Public Health
August 14, 2019
Mauricio Sadinle, an assistant professor of biostatistics from the University of Washington School of Public Health, received a two-year, $150,000 grant from the National Science Foundation to develop tools to identify and link information on individuals who appear in different datasets.
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