Presentation: Opportunities and Challenges in the Analysis of Cancer Genomic Data
Speaker: Chad He, PhD, Associate Member, Public Health Sciences Division, Fred Hutchinson Cancer Research Center
Abstract: Cancer research is heavily driven by newly generated genomic data, such as somatic mutations, SNPs, and T-cell receptor profiling. Recent advances in technology have made it feasible to evaluate the association between genetic variants and cancer-related traits in large sample sizes. However, the analysis of these data has proved to be a challenging task due to data sparseness, high dimensions, and complex nature of cancer. In this talk, I will review the challenges and issues associated with the analysis of these data, and share some of our thoughts, approaches and explorations on the analysis of the data. Some emerging datasets and open questions will be briefly discussed as well.