PhD Statistical Genetics Pathway

Prerequisites

  • Familiarization with the Statistical Genetics Program
  • GENOME 371: Introductory Genetics (or equivalent class from another institution)
  • One of either GENOME 372: Genomics and Proteomics, GENOME 453: Genetics of the Evolutionary Process, or GENOME 465: Advanced Human Genetics (or equivalent class from another institution)

Required Courses: PhD - Statistical Genetics Pathway

BIOST 514 Biostatistics I
BIOST 515 Biostatistics II
BIOST 533 Theory of Linear Models
BIOST 550 Statistical Genetics I: Medelian Traits
BIOST 551 Statistical Genetics II: Quantitative Traits
BIOST 552 Statistical Genetics III: Design and Analysis
BIOST 570 Advanced Regression Methods for Independent Data
BIOST 581 Statistical Genetics Seminar
BIOST 590 Biostatistical Consulting
BIOST 800 Doctoral Dissertation
GENOME 540 Introduction to Computational Molecular Biology: Genome and Protein Sequence Analysis
GENOME 562 Population Genetics
STAT 512 Statistical Inference
STAT 513 Statistical Inference
STAT 581 Advanced Theory of Statistical Inference
STAT 582 Advanced Theory of Statistical Inference
STAT 583 Advanced Theory of Statistical Inference
  • A new student placement exam may be taken to waive STAT 512 / STAT 513.
  • 9 quarters of BIOST 581 (Stat Gen Seminar) are required.
  • 36 credits of BIOST 800 (dissertation) are required.
  • Elective credits: 6 credits from Elective List One and 9 credits from Elective List Two.
    • Students are required to take one course (3 credits) in epidemiology. This can be satisfied by taking a BIOST course that is cross-listed with Epidemiology (e.g., BIOST 516, BIOST 519, BIOST 531, BIOST 536, BIOST 537, BIOST 555) as well as EPI 517 (cross-listed with PHG511). Note: a BIOST course that is cross-listed with EPI and listed under Elective List 1 may count towards both the elective credit and the epidemiology requirement.
    • Any of the approved Statistical Genetics prerequisites: GENOME 361, GENOME 371 (Intro Genetics or equivalent), GENOME 372 (Genomics & Proteomics), GENOME 453 (Genetics of the Evolutionary Process), GENOME 465 (Advanced Human Genetics or equivalent) can be used to satisfy Elective List 2 requirements.
    • Biological oriented Stat Gen requirements (e.g., GENOME 541, GENOME 562) may count for both a core requirement and Elective List 2 requirement.
    • BIOST 571 and BIOST 572 (which is required for Standard Pathway students) may count as Elective List One credits for Stat Gen students.
  • GENOME 541 may be substituted for GENOME 540, but both may not be used.
  • Minimum 3.0 grade in each required course and 2.7 minimum in each elective course. Elective courses may be taken S/NS. To earn the grade of "S," students must achieve a 2.7 or higher.
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Additional Course Recommendations
  • In preparation for work on their Dissertation, students are expected to master research, presentation, and computational skills at the level covered in BIOST 561BIOST 562, and BIOST 563. Taking these courses in the first year of PhD studies is recommended.
  • In preparation for advanced coursework in Statistical Theory (STAT 581, STAT 582, and STAT 583) and the PhD Statistical Theory Exam, students are expected to master Real Analysis and Measure Theory at the level covered in MATH 574MATH 575, and STAT 559. Taking these courses in the first year of PhD studies is recommended, for students who have not previously mastered this material.
  • In preparation for the PhD Applied Statistics Exam, students are expected to master data analysis at the level covered in BIOST 579. Taking this course at least once in the second year of PhD studies is recommended.
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    Examination and Dissertation Requirements
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    Selecting the Pathway

    Students must email the Graduate Program (biostgp@uw.edu) to notify of their wish to follow the Statistical Genetics PhD Pathway Degree.

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    Department Expectations

    Expectations for All Students
    All students in the Department of Biostatistics are expected to participate in the annual Department Retreat, usually held in mid-September.

     

    Student Progress Expectations for PhD Students
    Year 1:
    Get a minimum grade of 3.0 in BIOST 514/515, 533, and STAT 512/513
    Take at least one List 1 or List 2 Elective Spring Quarter with a minimum grade of 2.7
    Take MS Theory Exam
    Take BIOST 563 Summer Quarter

    Year 2:
    Get a Minimum grade of 3.0 in STAT 580’s and BIOST 570’s (BIOST 570 only for Stat Gen)
    Take and Pass PhD Qualifying Exams

    Year 3:
    Identify Dissertation Advisor Autumn Quarter
    Start Dissertation Credits (BIOST 800) no later than Winter Quarter
    Form Dissertation (Supervisory) Committee no later than Spring Quarter
    Complete TA, Consulting class, and many of the List 1 and List 2 Electives

    Year 4:
    Complete all PhD Graduate Program Requirements
    Take and Pass General Exam

    Year 5:
    Take and Pass Final Exam and Complete Dissertation

     

    Department Policy on Waiving Course Requirements
    In order to facilitate more rapid progress through the programs of study administered by the Department of Biostatistics, the departmental faculty will consider petitions for waiving required coursework as described by the policy guidelines given below.

    General Policy

    The overarching principles of this policy are:

    • That the students, through prior comparable coursework at other institutions, have acquired mastery of the overwhelming majority of material taught in the course to be waived,
    • That the students will pursue more advanced coursework in the general area of the course being waived,
    • That by waiving the coursework, the students will be able to make more rapid progress toward completion of the degree, and
    • That any decision to grant the petition for a waiver will be formally documented by the students’ academic advisors, a committee administering a placement exam and/or the current instructors for the course, and the graduate program office for the department. Such documentation must be completed prior to the quarter that the student would normally take the waived course.
    • In general, no students will be allowed a waiver of the requirements to take the advanced core courses in the PhD pathway. Hence: all PhD students are required to take STAT 581-582-583 and BIOST 570. Students in the Standard Pathway are required to take BIOST 571-572. Students in the Statistical Genetics Pathway are required to take BIOST 550-551-552.
    • In general, no students will be allowed a waiver of the requirements for biostatistical consulting (BIOST 590).
    • In general, no students will be allowed a waiver of the requirements for 9 credits in departmental seminars (BIOST 580 or BIOST 581, depending on pathway).
    • In general, no students will be allowed a waiver of the requirement for electives with a methodologic emphasis (Elective List One).
    • In general, no students will be allowed a waiver of the requirement for electives with a biology or public health emphasis (Elective List Two), except as noted for the Statistical Genetics Pathway, where some prerequisite courses and required courses in genetics and genome sciences can be used to satisfy these requirements.

    A student who enters the program with a prior master’s degree in statistics or biostatistics can petition to have selected first year required core coursework waived.
    a. The conditions under which each specific course might be waived will need to be approved by: 1) the student’s academic advisor, 2) a committee administering a placement exam and/or the current instructor of the course to be waived, and 3) the graduate program office. b. Typical conditions under which each specific course might be waived are provided below.

    Only in the most extraordinary circumstances can the above general policy be waived for an individual student, and then only if agreed by the faculty as a whole.

    Conditions for Waiving Specific Courses

    • BIOST 514/515 - Students entering the PhD program may petition for the requirements for BIOST 514/515 to be waived if all of the following are agreed to by the academic advisor, the current instructor of BIOST 514, and the departmental graduate program office:
      1) The student has a master’s degree in biostatistics or statistics or the equivalent from another institution
      2) The student’s curriculum at that other institution included comparable coursework that covered the overwhelming majority of the material taught in BIOST 514/515
      3) The student will instead take BIOST 536/537 or similar courses with an applied emphasis (any of these courses may count as List 1 electives with a methodologic emphasis).
    • STAT 512/513 - Students entering the PhD program may petition for the requirements for STAT 512/513 to be waived if all of the following are agreed to by the academic advisor, a committee administering a placement exam, and the departmental graduate program office:
      1) The student has a master’s degree in biostatistics or statistics or the equivalent from another institution
      2) The student’s curriculum at that other institution included comparable coursework that covered the overwhelming majority of the material taught in STAT 512/513 and at the level of rigor it is taught at the University of Washington
      3) The student has passed the MS theory placement exam at the PhD level
      4) The student has the necessary mathematical and statistical knowledge to proceed directly to take STAT 581/582/583 instead.
    • BIOST 533 - Students entering the PhD program may petition for the requirements for BIOST 533 to be waived if all of the following are agreed to by the academic advisor, the most recent instructor of BIOST 533, and the departmental graduate program office:
      1) The student has a master’s degree in biostatistics or statistics or the equivalent from another institution
      2) The student’s curriculum at that other institution included comparable coursework that covered the overwhelming majority of the material taught in STAT 533 and at the level of rigor it is taught at the University of Washington
      3) The student has the necessary mathematical and statistical knowledge to proceed directly to instead take BIOST 570 during his/her first year in the program (this will generally mean that the student has also waived STAT 512/513 and BIOST 514/515).